BMJ 2006;333 (14 October), doi:10.1136/bmj.333.7572.0-c
Read industry supported drug reviews with caution
Industry supported meta-analyses are of inferior quality to Cochrane meta-analyses of the same drugs. Jørgensen and colleagues (p 782) systematically compared the methodology and conclusions of 24 Cochrane meta-analyses with industry supported meta-analyses and other meta-analyses that studied the same two drugs in the same disease. Cochrane reviews were more transparent and more often considered the potential for bias than industry supported reviews, which always recommended the drug without reservation. Reviews with no, undeclared, and not for profit support had similarly cautious conclusions to matched Cochrane reviews.
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- Cochrane reviews compared with industry supported meta-analyses and other meta-analyses of the same drugs: systematic review
- Anders W Jørgensen, Jørgen Hilden, and Peter C Gøtzsche
BMJ 2006 333: 782.[Abstract] [Full Text] [PDF]
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