BMJ 2006;333 (5 August), doi:10.1136/bmj.333.7562.0
Antibiotics for acute purulent rhinitis-wait and watch
Antibiotics should not be used as first line treatment for acute purulent rhinitis because of their gastrointestinal toxicity, even though they are probably effective. Arroll and Kenealy (p 279) conducted a meta-analysis of seven randomised controlled trials in adults and children. The relative risks for benefits and harms with the antibiotics were 1.18 and 1.46 respectively. Antibiotics may be used when the symptoms continue long enough to concern patients, the authors add.
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Related Article
- Are antibiotics effective for acute purulent rhinitis? Systematic review and meta-analysis of placebo controlled randomised trials
- B Arroll and T Kenealy
BMJ 2006 333: 279.[Abstract] [Full Text] [PDF]
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