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BMJ 2006;332:701 (25 March), doi:10.1136/bmj.332.7543.701-b
A last minute change made by editorial staff in this editorial by James P Neilson and Zarko Alfirevic resulted in an error in describing the detection of Down's syndrome (BMJ 2006;332:433-4, 25 Feb). The statement in the fifth paragraph that refers to full karyotyping "picking up more truly positive cases of Down's syndrome" is wrong. In fact, qf-PCR (quantitative fluorescent polymerase chain reaction) will detect all true cases of Down's syndrome.
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