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BMJ 2006;332 (4 March), doi:10.1136/bmj.332.7540.0-d
Stress at work is an important risk factor for metabolic syndrome. In a prospective cohort study by Chandola and colleagues (p 521), more than 10 000 men and women employed in 20 London civil service departments and aged 35-55 at baseline were followed up for an average of 14 years. Employees with chronic work stress were more than twice as likely to develop metabolic syndrome than those without work stress (odds ratio 2.25, 95% CI 1.31 to 3.85). This provides evidence for the biological plausibility of the link between psychosocial stressors from everyday life and heart disease, say the authors.
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