BMJ  2006;332 (11 February), doi:10.1136/bmj.332.7537.0-d

Case reports of suspected adverse drug reactions are of limited value

Published case reports of suspected adverse drug reactions are of questionable value, as the suspected reactions are seldom subjected to further verification. Loke and colleagues (p 335) carried out a systematic follow-up of 63 adverse drug reaction reports published in 1997 in five medical journals and found that the vast majority (83%) of the suspected reactions had not been subjected to additional rigorous evaluation after five years. Details of the suspected reactions also failed to be consistently incorporated into commonly used drug information sources.


Figure 1
 Credit: PHOTOS.COM

 


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Relevant Article

Case reports of suspected adverse drug reactions—systematic literature survey of follow-up
Yoon Kong Loke, Deirdre Price, Sheena Derry, and Jeffrey K Aronson
BMJ 2006 332: 335-339. [Abstract] [Full Text] [PDF]

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