BMJ 2006;332 (7 January), doi:10.1136/bmj.332.7532.0
Role of gastro-oesophageal reflux treatment for chronic cough may be in doubt
Interventions to reduce chronic cough associated with gastro-oesophageal reflux may be less beneficial than international guidelines suggest because trialists may have misdiagnosed chronic non-specific cough. In a systematic review and meta-analysis of randomised controlled trials, Chang and colleagues (p 11) found that this uncertainty sheds doubt on the effectiveness of proton pump inhibitors for treating cough associated with gastro-oesophageal reflux disease.
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- Systematic review and meta-analysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux
- A B Chang, T J Lasserson, T O Kiljander, F L Connor, J T Gaffney, and L A Garske
BMJ 2006 332: 11-17.[Abstract] [Full Text] [PDF]
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