BMJ  2005;331 (19 November), doi:10.1136/bmj.331.7526.0-a

Women with treated CIN remain at increased risk of cervical and other cancers

In the first 20 years after treatment for cervical intraepithelial neoplasia (CIN) the risk of cervical cancer, and of most other gynaecological and smoking related cancers, is higher than in the average population. In a retrospective cohort study including more than 7500 women treated for CIN between 1974 and 2001 (p 1183), Kalliala and colleagues found that the peak incidence of invasive cervical cancer was during the second decade after treatment. They also observed that even women with low grade lesions are at increased risk of developing invasive cancer.

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Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia: retrospective cohort study

Ilkka Kalliala, Ahti Anttila, Eero Pukkala, and Pekka Nieminen
BMJ 2005 331: 1183-1185. [Abstract] [Full Text] [PDF]

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