BMJ  2005;331 (16 July), doi:10.1136/bmj.331.7509.0-e

Re-examining SSRIs for depression

In a clinical review on page 155, Moncrieff and Kirsch take a close look at available evidence for and against the use of selective serotonin reuptake inhibitors (SSRIs) in treating depression. Current approaches to depression should be re-evaluated, they say, and alternatives to drug treatment should be developed further. Since antidepressants have become society's main response to distress, the authors say that expectations raised by decades of use will also need to be addressed.

Credit: CRISTINA PEDRAZZINI/SPL

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