BMJ  2005;331 (16 July), doi:10.1136/bmj.331.7509.0-a

Treating ocular hypertension and glaucoma pays off

Reducing intraocular pressure in patients with ocular hypertension or manifest glaucoma reduces the risk of visual impairment in the long term. In a systematic review and a meta-analysis of randomised controlled trials, Maier and colleagues (p 134) showed that 12 patients need to be treated for ocular hypertension in order to prevent one case of progression to glaucoma (hazard ratio 0.56, 95% confidence interval 0.39 to 0.81, compared to non-treatment). Treating seven patients with hypertensive or normotensive manifest glaucoma significantly delayed deterioration of visual field in one patient (0.65, 0.49 to 0.87).

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Relevant Article

Treatment of ocular hypertension and open angle glaucoma: meta-analysis of randomised controlled trials

Philip C Maier, Jens Funk, Guido Schwarzer, Gerd Antes, and Yngve T Falck-Ytter
BMJ 2005 331: 134. [Abstract] [Full Text] [PDF]

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