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BMJ 2005;330 (11 June), doi:10.1136/bmj.330.7504.0-d
Obesity in middle adulthood increases the risk of dementia later in life, independently of comorbid conditions. In a 27 year prospective longitudinal population based study that included 10 276 men and women, Whitmer and colleagues (p 1360) found that, in comparison to people with normal body mass index, obese people had a 74% greater risk of dementia and overweight people had a 35% greater risk. Similar results were obtained from analyses comparing skinfold thickness.
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