BMJ 2005;330 (7 May), doi:10.1136/bmj.330.7499.0-e
Allocation concealment is neglected in papers and protocols
Allocation concealment is inadequately reported in most published randomised controlled trials, as well as in the corresponding trial protocols. In a cohort study of 102 sets of publications and trial protocols approved by the scientific and ethical committees for Copenhagen and Frederiksberg, Pildal and colleagues (p 1049) found that allocation concealment was not clearly reported in 96 out of 102 published articles. Protocols of only 15 of these 96 trials had adequate allocation concealment (16%, 95% confidence interval 9% to 24%).
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- Comparison of descriptions of allocation concealment in trial protocols and the published reports: cohort study
- Julie Pildal, An-Wen Chan, Asbjørn Hróbjartsson, Elisabeth Forfang, Douglas G Altman, and Peter C Gøtzsche
BMJ 2005 330: 1049.[Abstract] [Full Text] [PDF]
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