BMJ  2005;330 (7 May), doi:10.1136/bmj.330.7499.0-a

For newly diagnosed ischaemic heart disease give a statin, aspirin, and blocker

Combinations of statins, aspirins, and blockers are associated with the greatest reduction in all cause mortality in patients with a first diagnosis of ischaemic heart disease. In a case-control analysis including 13 029 patients nested within an open prospective cohort study with 1.18 million patients, Hippisley-Cox and Coupland (p 1059) compared odds ratios for risk of death in patients with heart disease who were on different treatment regimens. The addition of an angiotensin converting enzyme inhibitor conferred no additional benefit despite adjusting the analyses for the presence of congestive heart failure.

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Effect of combinations of drugs on all cause mortality in patients with ischaemic heart disease: nested case-control analysis

Julia Hippisley-Cox and Carol Coupland
BMJ 2005 330: 1059-1063. [Abstract] [Full Text] [PDF]

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