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BMJ 2005;330 (12 March), doi:10.1136/bmj.330.7491.0
Women who are at increased risk of developing pre-eclampsia can be identified at the time of antenatal booking. Reviewing 52 studies, Duckitt and Harrington (p 565) found that the most important risk factors for developing pre-eclampsia are a previous history and the presence of antiphospholipid antibodies. Pre-existing diabetes and a body mass index of 35 or more before pregnancy almost quadruple the risk; pre-existing hypertension, renal disease, chronic autoimmune disease, and 10 or more years between pregnancies increase the risk of developing pre-eclampsia to a lesser degree.
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Credit: MOTHER & BABY/IAN HOOTON
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