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BMJ 2005;330 (8 January), doi:10.1136/bmj.330.7482.0-c
The public, rather than trial participants, will likely bear many of the consequences of latent risks associated with gene transfer. On page 79, Kimmelman reviews recent developments in gene transfer in humans, focusing on the risks in such clinical trials, especially for healthy trial participants. He argues that uncertainties of risks demand central ethical review of all trial protocols and emphasises that so far only the United Kingdom and Australia have implemented measures to track the health of trial participants in the long term.
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