BMJ 2004;329 (11 December), doi:10.1136/bmj.329.7479.0
Treat migraine with parenteral metoclopramide
Parenteral metoclopramide is a highly effective treatment for migraine headaches and should be the drug of first choice for treatment of acute migraine in emergency departments. Colman and colleagues (p 1369) performed a meta-analysis of 13 eligible trials including 655 adults. Metoclopramide was almost three times as effective as placebo in relieving migraine pain, and only four patients need to be treated with metoclopramide to enable one additional patient to achieve significant reduction in pain.
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Credit: JIM DOWDALLS/SPL
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- Parenteral metoclopramide for acute migraine: meta-analysis of randomised controlled trials
- Ian Colman, Michael D Brown, Grant D Innes, Eric Grafstein, Ted E Roberts, and Brian H Rowe
BMJ 2004 329: 1369.[Abstract] [Full Text] [PDF]
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