BMJ 2004;329 (6 November), doi:10.1136/bmj.329.7474.0-a
Paternal aging raises risk of schizophrenia
Children fathered by older men with no family history of schizophrenia are more likely than the children of younger men to develop schizophrenia. Analysing a cohort of 754 330 people born in Sweden between 1973 and 1980 and living in Sweden at age 16, Sipos and colleagues (p 1070) found that the overall hazard ratio for each 10 year increase in paternal age was 1.47 (95% confidence interval 1.23 to 1.76). They say that accumulation of sperm mutations might lead to this increased risk.
|
|
Credit: DAN WEAKS/PHOTONICA
|
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
StumbleUpon 
Technorati What's this?
Relevant Article
- Paternal age and schizophrenia: a population based cohort study
- Attila Sipos, Finn Rasmussen, Glynn Harrison, Per Tynelius, Glyn Lewis, David A Leon, and David Gunnell
BMJ 2004 329: 1070.[Abstract] [Full Text] [PDF]
This Article
- Respond to this article
- Alert me when this article is cited
- Alert me when responses are posted
- Alert me when a correction is posted
Services
- Email this article to a friend
- Find similar articles in BMJ
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
Related Content
Bookmark with
What's new
Latest blogs
Find BMJ on:
Services
Tools
Online poll
Resources
Rapid responses for this article
There are no rapid responses for this article. Print issues
