BMJ  2004;329 (4 September), doi:10.1136/bmj.329.7465.0-d

Taking lactobacillus does not prevent vulvovaginitis

Lactobacillus preparations taken orally or vaginally during and for four days after antibiotics were not effective in preventing post-antibiotic vulvovaginitis. Pirotta and colleagues (p 548) randomised 273 women aged 18-50 who had started short term treatment with oral antibiotics for non-gynaecological infections giving them lactobacillus orally or vaginally, or both, or standard care in association with their antibiotic treatment. They found that, overall, 23% of the women developed post-antibiotic vulvovaginitis; compliance was high, but lactobacillus treatment was ineffective.

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Effect of lactobacillus in preventing post-antibiotic vulvovaginal candidiasis: a randomised controlled trial

Marie Pirotta, Jane Gunn, Patty Chondros, Sonia Grover, Paula O'Malley, Susan Hurley, and Suzanne Garland
BMJ 2004 329: 548. [Abstract] [Full Text] [PDF]