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BMJ 2004;329 (4 September), doi:10.1136/bmj.329.7465.0-b
Alcohol drinking habits in middle age affect the risk of cognitive impairment in old age. In Finland, Anttila and colleagues (p 539) re-examined 1464 men and women aged 65-79 after an average follow up of 23 years, and found that participants who drank no alcohol in midlife as well as those who drank alcohol frequently were twice as likely to have mild cognitive impairment in old age than those who drank alcohol infrequently. People who were carriers of the apolipoprotein e4 allele had an increased risk of dementia with increasing alcohol consumption.
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Credit: CLIVE BARDA/TOPFOTO
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