(Posted as supplied by authors)

Uterine Rupture: Supplementary Table of Included Studies

Study	Purpose of Study	Population	Sample Size	Uterine exploration	Reported outcomes	Reported associated major morbidty
Meehan 1989¹⁸	Compare risk between of trial of labor and planned cesarean delivery after a previous cesarean.	TOL-One prior CD ERCD- One or more prior CDs	I- 127 A- 217 SL- 162 ERCD- 430	NR	Symptomatic UR: TOL- 1 Asymptomatic UR: TOL- 5	Symptomatic UR: 0 perinatal deaths 0 maternal deaths
Blanchette 1999²³	To compare PGE1 (misoprostol) to PGE2 (dinoprostone) for cervical ripening and induction in a community hospital.	One or more LTCD, not clear what was done with unknown	PGE1- 16 PGE2- 9	NR	Symptomatic UR: PGE1- 3 Symptomatic UR: PGE2- 0	Symptomatic UR: PGE1- 0 maternal deaths, 1 perinatal death, 3 hysterectomies
Flamm 1987²⁴	To compare the use of oxytocin for trial of labor in patients with one or more previous cesarean deliveries.	LTCD and unknown and more than 1 prior	IA- 485 SL- 1291	NR	Symptomatic UR: IA- 2 SL- 1 Asymptomatic UR: IA-5 SL- 6	Symptomatic UR: Overall- 0 maternal deaths, insufficient detail for UR-related perinatal deaths or hysterectomies
Flamm 1997²⁵	Evaluate the use of PGE2 for cervical ripening in patients with prior CD	LTCD and unknown and more than 1 prior	IA- 453 SL-4569	Discretion	Symptomatic UR: IA- 6 SL- 33	Symptomatic UR: Overall- Insufficient detail for UR-related maternal deaths, perinatal deaths, or hysterectomies
Blanco 1992²⁶	Determine safety and efficacy of induction with PGE2 in patients with a prior low transever CD	One prior LTCD	IA- 25 SL- 56	NR	Symptomatic UR: IA-0 SL- 0 Asymptomatic UR: IA- 0 SL- 0	NA
Connolly 2001²⁷	Identify risk factors for scar dehiscence in labor.	Cases: 1 prior LTCD or low vertical CD who underwent TOL with dehiscence Controls: one prior LTCD or low vertical CD who underwent TOL without dehiscence	Cases: 13 Controls: 13	NR	8 partial dehiscence 5 complete dehiscence	0 maternal deaths, 0 perinatal deaths, 0 hysterectomies
Leung 1993²⁸	Identify risk of uterine rupture in a trial of labor after a previous cesarean delivery.	Cases: patients with prior CD and UR while undergoing subsequent TOL Controls: patients with prior CD and subsequent TOL and no UR during same time, randomly selected, grouped by year (More than one and unknown allowed)	Cases: 70 Controls: 70	Yes	Symptomatic UR: 70	NR
Leung 1993²⁹	Identify risk factors associated with overt, catastrophic uterine rupture after previous cesarean delivery.	Case series of all cases of uterine rupture after a previous cesarean delivery	99 URs	NR	Symptomatic UR: 99	Symptomatic UR: 1 maternal death, 6 perinatal deaths, 19 hysterectomies, 29 transfusions.
Bujold 2002³⁰	Evaluate factors associated with neonatal disease and death caused by uterine rupture in patients undergoing a trial of labor after previous cesarean delivery.	Case series of symptomatic UR following TOL after LTCD	23 Urs	NR	Symptomatic UR: 23	Symptomatic UR: 1 perinatal death, 3 hypoxicischemic encephalopathies
Smith 2002¹¹	Determine risk of intrapartum still birth or neonatal death between trial of labor after previous cesarean delivery and planned repeat cesarean delivery.	Singleton pregnancies between 37-42 weeks, cephalic, without lethal congenital anomalies, one or more prior CD, not clear what was done with unknown and low vertical	SL/IA- 15515 ERCD- 9014	NR	NA	Perinatal Death due to mechanical-TOL- 7 ERCD- 0 Mechanical-uterine rupture, cord compression (including prolapse), birth trauma, or asphysixa associated with disproportion.