BMJ  2004;328 (17 April), doi:10.1136/bmj.328.7445.0

Risk of complications in type 1 diabetes pregnancies remain high

Even though women with type 1 diabetes are planning their pregnancies, achieving good glycaemic control early, and taking folic acid, they are at high risk of maternal, perinatal, and neonatal complications. In a nationwide cohort study in the Netherlands, Evers and colleagues (p 915) tracked the outcomes of 323 pregnant women with type 1 diabetes and found that, relative to all pregnant women, the rates of pre-eclampsia, preterm delivery, caesarean section, maternal mortality, congenital malformations, perinatal mortality, and macrosomia were greatly increased. Neonatal morbidity, especially hypoglycaemia, occurred in 80% of pregnancies in diabetic women. The authors conclude that near optimal maternal glycaemic control (HbA_1c 7.0%) does not seem to be good enough.

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Relevant Article

Risk of complications of pregnancy in women with type 1 diabetes: nationwide prospective study in the Netherlands

Inge M Evers, Harold W de Valk, and Gerard H A Visser
BMJ 2004 328: 915. [Abstract] [Full Text] [PDF]

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