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BMJ 2004;328:884 (10 April), doi:10.1136/bmj.328.7444.884-a
lactam does not improve results
In this summary in This Week in the BMJ (of the paper by Mical Paul and colleagues, "
lactam monotherapy versus
lactam-aminoglycoside combination therapy for sepsis in immunocompetent patients: systematic review and meta-analysis of randomised trials," pp 668-672) a vital word was wrong. The first sentence should read: "In patients with sepsis but without [not "with"] neutropenia, mortality is no different whether
lactams and aminoglycosides are used together or
lactams are used alone, although the risk of adverse effects is increased with
lactams and aminoglycosides." And, as you will have noticed, we also slipped up on the spelling of aminoglycoside in the summary's title.
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