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BMJ 2004;328 (6 March), doi:10.1136/bmj.328.7439.0-e
Randomised drug policy trials are feasible, and they may produce results in a short time, which are likely to concord with observational evaluations. Schneeweiss and colleagues (p 560) compared results of studies investigating the health effects of a new reimbursement policy for nebulised respiratory drugs. The randomised policy trial and an observational time trend analysis had similar results. Randomised policy trials provide rigorous results almost as soon as the data become available, avoiding the time delay caused by identifying controls and adjusting for confounding.
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