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Prolonged antithrombotics do not improve unstable coronary syndrome

BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7435.0-f (Published 05 February 2004) Cite this as: BMJ 2004;328:0-f

Question Is a prolonged period of antithrombotic pretreatment effective for reducing adverse outcomes in patients with unstable coronary syndromes?

Synopsis Because of the risk associated with percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery in patients with unstable coronary syndromes, some experts have recommended an extended period of antithrombotic therapy (“cooling off”) before intervention. In this single blinded, randomised controlled trial, eligible patients had symptoms of unstable angina plus either ST segment depression or …

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