BMJ  2004;328 (24 January), doi:10.1136/bmj.328.7433.0-b

Electrocautery strategy can induce ovulation in polycystic ovary syndrome

In women with clomiphene citrate resistant polycystic ovary syndrome, an integrated electrocautery strategy results in equivalent pregnancy rates but fewer multiple pregnancies than when gonadotrophin hormones alone are used. Bayram and colleagues (p 192) randomised 168 women to an electrocautery strategy—consisting of laparoscopic electrocautery of the ovaries, clomiphene, and additional hormones if required—or gonadotrophin hormones alone to induce ovulation. The ongoing pregnancy rate in both groups was 67% at 12 months, but treatment with recombinant follicle stimulating hormone alone resulted in more multiple pregnancies. Electrocautery therapy and clomiphene citrate before gonadotrophin hormones is as effective as hormones alone and may reduce multiple pregnancies, the authors say.

Credit: MOTTA AND MAKABE/SPL


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Relevant Article

Using an electrocautery strategy or recombinant follicle stimulating hormone to induce ovulation in polycystic ovary syndrome: randomised controlled trial
Neriman Bayram, Madelon van Wely, Eugenie M Kaaijk, Patrick M M Bossuyt, and Fulco van der Veen
BMJ 2004 328: 192. [Abstract] [Full Text] [PDF]




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