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BMJ 2004;328 (24 January), doi:10.1136/bmj.328.7433.0-b
In women with clomiphene citrate resistant polycystic ovary syndrome, an integrated electrocautery strategy results in equivalent pregnancy rates but fewer multiple pregnancies than when gonadotrophin hormones alone are used. Bayram and colleagues (p 192) randomised 168 women to an electrocautery strategyconsisting of laparoscopic electrocautery of the ovaries, clomiphene, and additional hormones if requiredor gonadotrophin hormones alone to induce ovulation. The ongoing pregnancy rate in both groups was 67% at 12 months, but treatment with recombinant follicle stimulating hormone alone resulted in more multiple pregnancies. Electrocautery therapy and clomiphene citrate before gonadotrophin hormones is as effective as hormones alone and may reduce multiple pregnancies, the authors say.
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Credit: MOTTA AND MAKABE/SPL
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