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BMJ 2003;327 (29 November), doi:10.1136/bmj.327.7426.0-f
Current scoring methods for coronary heart disease may overestimate risk. Brindle and colleagues (p 1267) prospectively studied 6643 men participating in the British regional heart study and found that scoring methods derived from the Framingham study overpredicted risk by about 50%. The scores could be adjusted by dividing the calculated score by the amount of overprediction observed. This would improve predictive accuracy in the British population, but further refinements are required if treatment decisions are to be optimal.
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