BMJ 2003;327 (11 October), doi:10.1136/bmj.327.7419.0
Compliance therapy does not improve drug adherence in schizophrenia
Pragmatic talking therapy designed to improve adherence to drug treatment in schizophrenia patients fails. O'Donnell and colleagues (p 834) randomised 56 schizophrenia patients either to compliance therapy, a cognitive behavioural based motivational and psychoeducational intervention, or to non specific counselling. They found that adherence at one year was no better among patients in the intervention group, nor did patients' symptoms or quality of life improve. They also found that patients' attitudes to treatment strongly predicted later adherence.
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- Compliance therapy: a randomised controlled trial in schizophrenia
- Colin O'Donnell, Gary Donohoe, Louise Sharkey, Nicholas Owens, Maria Migone, Raewynn Harries, Anthony Kinsella, Conall Larkin, and Eadbhard O'Callaghan
BMJ 2003 327: 834.[Abstract] [Full Text] [PDF]
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