Table B

Table A Codes used in the ICD8 and ICD10 system for identifying patients with selected outcomes [As supplied by authors]
 

Outcome	ICD codes
Fractures	80099, 80100-80109, 80210-80299, 80399, 80500-80599, 81099, 81199, 81200-81299, 81300-81399, 81400-81409, 81500-81509, 81600-81604, 81899, 82000-82009, 82109-82199, 82300-82399, 82400-82409, 82500-82509, 82600-82609, 82799, S020-S029, S120-S129, S220-S221, S320-S328, S420-S429, S520-S529, S620-S628, S720-S729, S821-S829, S920-S929
Osteoporosis	72309, M800-M809, M810-M819
Kidney and urinary tract stones	59200-59209, N200-N209
Acute myocardial infarction	41009, 41099, I210-I219, I220-I229
Angina pectoris	41309, 41399, I200-I209
Cardiac arrhythmias	42720-42797, I440-I447, I450-I459, I470-I479, I489, I490-I499
Arterial hypertension	40199, I109
Heart failure	42709-42799, I500-I509
Stroke	43100-43199, 43309-43399, 43409-43499, 43690, I610-I619, I630-I639, I649
Gastric ulcers	53100-53199, 53209-53299, 53309-53399, 53409-53499, K250-K259, K260-K269, K270-K279, K280-K289
Acute pancreatitis	57700-57709, 57711-57719, K859, K861
Muscle pain	71709, 71799, M544-M549
Cancer	40.00-207.99, ICD10 codes starting with C and D00.0-D09.9
Psychiatric diseases	29000-29999, F000-F390
Neuroses	30000-30999, F400-F510
Parathyroid surgery codes	0842, 08420, 0844, 08440, 08450, 0846, 08460, 0856, 08560, 08570, KBBA10, KBBA20, KBBA30, KBBA40, KBBA50, KBBA70, and KBBA99

 

Table B Calculation of risk in surgically treated vs. conservatively treated with exclusion of those who had experienced an end-point before the time of diagnosis. The numbers in the columns "Surgery" and "No surgery" are number with end-point and total number [As supplied by author]
 

Parameter	Surgery	No surgery	Crude OR	HR of age (1)	HR of gender (2)	HR of surgery (3)
Fractures	204/1762	124/1103	1.03 (0.82-1.31)	2.13 (1.60-2.84)	1.97 (1.44-2.69)	0.76 (0.60-0.95)
Kidney stones	67/1637	23/1196	2.18 (1.36-3.48)	0.57 (0.37-0.88)	0.80 (0.50-1.28)	1.65 (1.02-2.65)
Stroke	120/1896	69/1233	1.14 (0.84-1.55)	6.49 (3.74-11.26)	0.86 (0.61-1.20)	0.81 (0.60-1.10)
Hypertension	81/1849	26/1221	2.11 (1.36-3.26)	1.16 (0.76-1.78)	0.74 (0.49-1.13)	1.48 (0.95-2.30)
AMI	86/1869	40/1204	1.40 (0.96-2.05)	3.84 (2.25-6.56)	0.50 (0.34-0.72)	1.03 (0.71-1.50)
Angina	81/1875	39/1229	1.38 (0.94-2.03)	2.78 (1.73-4.47)	0.40 (0.28-0.58)	0.97 (0.66-1.42)
Heart failure	80/1905	48/1237	1.09 (0.75-1.56)	6.37 (3.21-12.65)	0.87 (0.58-1.32)	0.81 (0.57-1.17)
Arrhythmias	82/1879	32/1229	1.71 (1.13-2.57)	2.45 (1.50-4.02)	0.65 (0.44-0.98)	1.28 (0.85-1.92)
Pancreatitis	10/1896	6/1270	1.12 (0.41-3.08)	0.53 (0.19-1.48)	0.39 (0.14-1.07)	0.82 (0.30-2.25)
Ulcers	59/1835	47/1223	0.83 (0.56-1.23)	2.51 (1.49-4.23)	0.74 (0.48-1.13)	0.60 (0.41-0.88)
Muscle pain	33/1911	24/1245	0.89 (0.53-1.52)	1.38 (0.73-2.61)	1.72 (0.84-3.55)	0.66 (0.39-1.13)
Osteoporosis	27/1899	24/1252	0.74 (0.42-1.28)	8.94 (2.16-37.00)	4.27 (1.33-13.75)	0.59 (0.34-1.03)
Cancer	220/1799	89/1160	1.68 (1.30-2.17)	2.84 (2.07-3.89)	0.72 (0.56-0.92)	1.24 (0.96-1.58)
Psychiatric dis.	43/1911	28/1250	1.00 (0.62-1.63)	2.77 (1.40-5.48)	0.92 (0.53-1.59)	0.76 (0.47-1.22)
Neuroses	17/1901	13/1243	0.85 (0.41-1.76)	0.57 (0.27-1.21)	2.44 (0.84-7.08)	0.64 (0.31-1.32)

(1) Hazard rate for the end-point in question of age group ³ 50 vs. <50 years at diagnosis in a Cox model, e.g. was the fracture risk 1.90 times higher in the age-group ³ 50 than in the age group <50 years, (2) Hazard rate in males versus females for the end-point in question, (3) Hazard rate in surgically treated versus conservatively treated. The hazard rates are mutually adjusted.