BMJ  2003;326 (21 June), doi:10.1136/bmj.326.7403.0-e

Fluticasone propionate reduces risk of relapse in atopic dermatitis

Fluticasone propionate cream or ointment, applied twice weekly as part of an emollient maintenance treatment, reduces the risk of relapse in patients with atopic dermatitis. Results from Berth-Jones and colleagues' randomised, double blind, placebo controlled, parallel group trial (p 1367) show that after initial stabilisation treatment, the risk of flares was significantly lower in the group applying fluticasone propionate twice weekly than in the placebo group. Median time to relapse was six weeks for emollient alone and more than 16 weeks for additional fluticasone propionate.

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Relevant Article

Twice weekly fluticasone propionate added to emollient maintenance treatment to reduce risk of relapse in atopic dermatitis: randomised, double blind, parallel group study

John Berth-Jones, Robert J Damstra, Stefan Golsch, John K Livden, Oliver Van Hooteghem, Fulvio Allegra, and Christine A Parker
BMJ 2003 326: 1367. [Abstract] [Full Text] [PDF]

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