BMJ  2003;326 (7 June), doi:10.1136/bmj.326.7401.0-b

Meta-analysis can effectively pool cost data for individual patients

Meta-analysis of data on costs of treatment for individual patients can be used if sample sizes of individual studies are small. Bower and colleagues (p 1247) pooled the results of four trials of counselling in primary care that were underpowered to detect differences that may be of economic importance. Despite variation in the methods of the trials, analysis of data on costs was possible. The authors say, however, that it is a matter of debate whether secondary analysis provides a reasonably accurate estimate to inform policy and practice.

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Relevant Article

Meta-analysis of data on costs from trials of counselling in primary care: using individual patient data to overcome sample size limitations in economic analyses

Peter Bower, Sarah Byford, Julie Barber, Jennifer Beecham, Sharon Simpson, Karin Friedli, Roslyn Corney, Michael King, and Ian Harvey
BMJ 2003 326: 1247-1250. [Abstract] [Full Text] [PDF]

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