Table 2 Level of smoking in spouse and deaths from selected causes among female never smokers in California cancer prevention study (CPS I) cohort, as of 1959 and 1972. For reference, 1960-98 death rate in deaths per 1000 person years adjusted to 1960 US population for attained ages 35-84 is given18


All 1959 participants, followed 1960-98

1959 participants aged >=50, followed 1960-98

Participants defined in 1972, followed 1973-98

Smoking in spouse and cause of death

No of deaths/No of participants

Age adjusted relative risk (95% CI)

Fully adjusted relative risk (95% CI)

No of deaths/No of participants

Age adjusted relative risk (95% CI)

No of deaths/No of participants

Age adjusted relative risk (95% CI)

Coronary heart disease (death rate 1.65/1000)













Never (1)*

1053/7399

1.00

1.00

891/4230

1.00

428/3090

1.00

Former (2)*

1059/6858

1.02 (0.93 to 1.11)

1.03 (0.94 to 1.13)

909/4424

0.98 (0.89 to 1.08)

772/5079

1.03 (0.92 to 1.16)

Current:















Pipe or cigar (3)*

389/2691

0.99 (0.88 to 1.11)

0.97 (0.86 to 1.10)

162/1735

0.97 (0.86 to 1.10)

24/173

0.99 (0.66 to 1.49)

1-9 cigarettes/day (4)*

183/1102

1.13 (0.97 to 1.33)

1.03 (0.86 to 1.23)

162/719

1.15 (0.97 to 1.36)

24/200

0.89 (0.59 to 1.34)

10-19 cigarettes/day (5)*

310/2117

1.03 (0.91 to 1.17)

0.99 (0.86 to 1.14)

272/1301

1.03 (0.90 to 1.18)

42/344

0.90 (0.66 to 1.24)

20 cigarettes/day (6)*

412/3288

1.04 (0.92 to 1.16)

1.02 (0.90 to 1.16)

309/1735

0.96 (0.84 to 1.10)

89/616

1.30 (1.04 to 1.64)

21-39 cigarettes/day (7)*

167/1646

0.95 (0.80 to 1.12)

0.88 (0.74 to 1.06)

127/792

0.95 (0.79 to 1.15)

25/239

1.14 (0.76 to 1.71)

>=40 cigarettes/day (8)*

72/841

0.83 (0.65 to 1.06)

0.80 (0.62 to 1.03)

49/399

0.74 (0.55 to 0.98)

20/211

0.89 (0.57 to 1.40)

Total of current smokers

1533/11685

1.01 (0.93 to 1.09)

0.97 (0.89 to 1.06)

1258/6681

0.98 (0.90 to 1.07)

224/1783

1.06 (0.90 to 1.25)

Ever

2592/18543

1.01 (0.94 to 1.08)

0.99 (0.92 to 1.08)

2167/11105

0.98 (0.91 to 1.06)

996/6862

1.04 (0.93 to 1.16)

8 level index

3645/25942

1.00 (0.98 to 1.01)

0.99 (0.97 to 1.00)

3058/15335

0.99 (0.97 to 1.01)

1424/9952

1.02 (0.98 to 1.05)

Lung cancer (death rate 0.08/1000)













Never

51

1.00

1.00

31

1.00

25

1.00

Former

51

1.08 (0.73 to 1.60)

1.04 (0.69 to 1.57)

33

1.02 (0.62 to 1.66)

39

0.92 (0.56 to 1.53)

Current

75

0.93 (0.65 to 1.33)

0.88 (0.60 to 1.28)

44

0.86 (0.54 to 1.36)

14

1.00 (0.52 to 1.92)

Ever

126

0.99 (0.72 to 1.37)

0.94 (0.66 to 1.33)

77

0.93 (0.61 to 1.41)

53

0.95 (0.59 to 1.53)

8 level index

177

0.97 (0.91 to 1.04)

0.97 (0.90 to 1.05)

108

0.98 (0.89 to 1.07)

78

0.99 (0.87 to 1.13)

Chronic obstructive pulmonary disease (death rate 0.08/1000)











Never

45

1.00

1.00

35

1.00

21

1.00

Former

50

1.17 (0.78 to 1.75)

1.24 (0.80 to 1.93)

37

1.01 (0.64 to 1.60)

36

1.00 (0.59 to 1.72)

Current

78

1.11 (0.77 to 1.60)

1.12 (0.74 to 1.69)

54

0.94 (0.61 to 1.44)

18

1.57 (0.84 to 2.96)

Ever

128

1.13 (0.80 to 1.58)

1.16 (0.80 to 1.70)

91

0.97 (0.66 to 1.44)

54

1.14 (0.69 to 1.89)

8 level index

173

0.99 (0.92 to 1.06)

0.98 (0.91 to 1.06)

126

0.97 (0.89 to 1.06)

75

1.06 (0.94 to 1.20)

* Values in parentheses are index level of environmental tobacco smoke.




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