Vitamin D three times a year can prevent fractures

Supplementation with vitamin D every four months for five years reduced the number of first fractures in men and women aged 65 and older living in the community. Trivedi and colleagues (p 469) found that supplementation with 100 000 IU oral vitamin D reduced the incidence of fracture by 22%. Most fracture prevention trials have focused on clinically defined high risk groups and women, and many effective interventions may not be feasible or cost effective in the general population. This simple, safe, and low cost intervention may reduce osteoporotic fractures in the general community.


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Relevant Article

Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial
Daksha P Trivedi, Richard Doll, and Kay Tee Khaw
BMJ 2003 326: 469. [Abstract] [Full Text] [PDF]

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