Sepsis treatment: one size does not fit all
Severe sepsis and septic shock are life threatening consequences
of infections and are the leading causes of death in intensive care
units. On page 262 Bochud and Calandra discuss the epidemiology, origins, and treatment of sepsis, which occurs when immune response to
invasive pathogens is poor. Gram negative, Gram positive, and fungal
infections account for the most cases, and over the past decades little
impact has been made in reducing mortality. Future treatment
possibilities include pathogen specific regimens, rather than "one
size fits all" strategies.
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- Science, medicine, and the future: Pathogenesis of sepsis: new concepts and implications for future treatment
- Pierre-Yves Bochud and Thierry Calandra
BMJ 2003 326: 262-266.[Extract] [Full Text] [PDF]
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