Parathyroidectomy doesn't cure renal stone disease

After surgical treatment for primary hyperparathyroidism, the risk of developing renal stones remains high for 10 years. In a case-control study Mollerup and colleagues compared the prevalence of stone development in patients and matched controls from the general population (p 807). Patients with primary hyperparathyroidism have an increased risk of stones as much as 10 years before diagnosis of primary hyperparathyroidism. After surgery, the risk is reduced but is still 8.3% higher than the background risk of the general population.

(Credit: ZEPHYR/SPL)

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Relevant Article

Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study

Charlotte L Mollerup, Peter Vestergaard, Vibe Gedsø Frøkjær, Leif Mosekilde, Peer Christiansen, and Mogens Blichert-Toft
BMJ 2002 325: 807. [Abstract] [Full Text] [PDF]