Childhood circumstances linked to cardiovascular disease

Adverse childhood socioeconomic circumstances are associated with an increased risk of cardiovascular disease in later life, but the mechanisms for this association are unclear. Lawlor and colleagues (p 805) investigated the associations between social class in childhood and adulthood and insulin resistance in a cohort of British women aged 60-79. They found that belonging to a manual social class in childhood and in adulthood was associated with insulin resistance, dyslipidaemia, and obesity, and that the independent association between childhood social class and insulin resistance was stronger than that between adult social class and insulin resistance.

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Relevant Article

Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health study

Debbie A Lawlor, Shah Ebrahim, and George Davey Smith
BMJ 2002 325: 805. [Abstract] [Full Text] [PDF]