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Birth weight of offspring is inversely related to mothers' insulin
resistance in older age, even though glucose intolerance during
pregnancy is associated with heavier offspring at birth. These results,
from a cross sectional study by Lawlor and colleagues (p 359), support
the hypothesis that genetic factors determining insulin resistance
explain at least part of the association between birth weight and
cardiovascular disease and diabetes in adulthood.

(Credit: NEIL BROMHALL/SPL)