Table 2.  Predictive factors for adult height gain in patients with growth hormone deficiency: final model


Variable*
Regression coefficientdagger (95% CI)
P value
No of patients in final modelDagger (r2) 1885 (0.58)
Patients' characteristics:
  Target height (SD score) 0.22 (0.19 to 0.25) <0.0001
  Birth weight (SD score) 0.11 (0.08 to 0.13) <0.0001
  Sex (male=1, female=0) -0.54 (-0.62 to -0.47) <0.0001
Baseline variables:
  Age (years) 0.31 (0.28 to 0.33) <0.0001
  Pubertal (yes=1, no=0) -0.19 (-0.26 to -0.11) <0.0001
  Bone age delay (years) 0.18 (0.15 to 0.20) <0.0001
  Weight (SD score) -0.19 (-0.23 to -0.14) <0.0001
  Log peak growth hormone concentration (µg/l) -0.08 (-0.13 to -0.03) 0.002
Treatment variables:
  Completion of treatment as scheduled (yes=1, no=0) -0.30 (-0.37 to -0.22) <0.0001
  Duration of treatment (years) 0.22 (0.19 to 0.25) <0.0001

SD=standard deviation.
* The model includes baseline height SD score, time interval between baseline and adult height measurements, and the interaction between these two variables; therefore, the model similarly predicts the factors for adult height itself (in SD).
dagger The regression coefficient represents the change in SD score per unit change in predictor.
Dagger The number of subjects corresponds to those with no missing value for any predictor variable.




Access jobs at BMJ Careers
Whats new online at Student 

BMJ