Scrutinising risk factor thresholds

Interventions to lower blood pressure, serum cholesterol, and other risk factors reduce the risk of cardiovascular disease regardless of initial levels. The goal, therefore, write Malcolm Law and Nicholas Wald (p 1570), should not be to "normalise" risk factors but simply to reduce them as much as possible. This means, they say, targeting everyone at high risk, as determined by age or known cardiovascular disease, rather than by the level of their risk factors.


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Relevant Article

Risk factor thresholds: their existence under scrutiny
M R Law and N J Wald
BMJ 2002 324: 1570-1576. [Extract] [Full Text] [PDF]

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