Anti-leukotrienes do not benefit asthma
Adding anti-leukotrienes to inhaled glucocorticoids produces a
non-significant reduction in the risk of an exacerbation of asthma and
cannot be recommended as a substitute for increasing the dose
of inhaled glucocorticoids. These finding are from a systematic review
of 13 trials by Francine Ducharme (p 1545) of the evidence on the
safety and efficacy of anti-leukotrienes as add-on therapy to inhaled
glucocorticoids. Until further evidence is available, the gold standard
treatment of asthma should remain the use of inhaled glucocorticoids.
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- Anti-leukotrienes as add-on therapy to inhaled glucocorticoids in patients with asthma: systematic review of current evidence
- Francine M Ducharme
BMJ 2002 324: 1545.[Abstract] [Full Text] [PDF]
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