Etoricoxib is effective in acute gouty arthritis

Inhibition of cyclo-oxygenase-2 with etoricoxib provides rapid and effective treatment for acute gouty arthritis. Schumacher and colleagues (p 1488) assessed the safety and efficacy of etoricoxib compared with indometacin, the standard treatment for acute gout. Etoricoxib showed comparable efficacy to indometacin for all end points measured, including patients' assessment of pain, and resulted in fewer drug related adverse experiences. This study, which shows that selective, potent, and rapid inhibition of cyclo-oxygenase-2 is sufficient to treat acute gouty arthritis effectively, may serve as a basis for future trial design.


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Relevant Article

Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritis
H Ralph Schumacher, Jr, Judith A Boice, David I Daikh, Saurabh Mukhopadhyay, Kerstin Malmstrom, Jennifer Ng, Guillermo A Tate, and Javier Molina
BMJ 2002 324: 1488-1492. [Abstract] [Full Text] [PDF]




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