Number (percentage) of alleles of C reactive protein found in cases of invasive pneumococcal disease and controls


Allele size (base pairs) Controls (n=345) Cases (n=205)

130 8 (1.2) 2 (0.5)
132 21 (3.0) 7 (1.7)
134 384 (55.6) 269 (65.6)*
136 22 (3.2) 10 (2.4)
138 2 (0.3) 2(0.5)
140 6 (0.9) 1 (0.25)
142 60 (8.7) 32 (7.8)
144 180 (26.1) 86 (21)
146 7 (1.0) 0
148 0 1 (0.2)
Total 690 410

* P=0.001 uncorrected, P=0.01 corrected for 10 comparisons.




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