Table 1. Probiotics studied in trials and patients with absence of diarrhoea at end of trial


Trial Probiotic Dose Duration of treatment Antibiotic studied % of patients without diarrhoea
Active group Placebo group

Adam et al3 S boulardii 4 capsules/day Variable Mixture 96 83
Gotz et al4 L acidophilus and L bulgaricus 1 sachet Lactinex four times a day 5 days Ampicillin 100 86
Surawicz et al5 S boulardii 1 g/day Variable Mixture 91 78
Wunderlich et al6 E faecium SF68 1 capsule twice a day 7 days Mixture 91 73
Tankanow et al7 L acidophilus and L bulgaricus 1 g Lactinex four times a day 10 days Amoxicillin 34 31
Orrhage et al8 L acidophilus and Bifidobacterium longum Fermented milk with cultures 250 ml twice a day 21 days Clindamycin 80 30
McFarland et al9 S boulardii 1 g/day 49 days Mixture 93 85
Lewis et al10 S boulardii 113 mg twice a day 14 days Mixture 79 83
Vanderhoof et al11 Lactobacillus GG 1-2 capsules a day (1010 colonies per capsule) 10 days Mixture 93 74




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