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Referral to specialist otolaryngologist may be advisable
EDITOR We agree that unilateral nasal blockage and bleeding warrant prompt
referral since these symptoms may indicate an underlying malignancy.
Contrary to the authors' suggestion, however, this is an uncommon
presentation of nasopharyngeal carcinoma, which is more frequently
associated with unilateral glue ear or cervical lymphadenopathy.
Examination of the nose by an experienced doctor using adequate
illumination is essential to exclude other diagnoses, such as septal
deflection, turbinate enlargement, and nasal polyposis. We are also
surprised that no mention is made of the diagnostic value of allergy
testing, which has been shown to be feasible in primary
care.2
With regard to treatment, the authors do not emphasise that topical
nasal decongestants such as oxymetazoline should be avoided in
prolonged courses owing to the incidence of rebound oedema and rhinitis
medicamentosa.3 We disagree with the assertion that
steroid drops should not be used in chronic allergic rhinitis since
they increase systemic absorption.
Betamethasone nasal drops do cause appreciable systemic bioavailability
and in protracted regimens have been associated with undesirable side
effects. This is not the case, however, with fluticasone nasal drops,
which have negligible absorption (0.06%), less even than fluticasone
spray (0.51%).4 Along with budesonide, they do not
contain benzalkonium chloride preservative, which is found in most
other topical preparations and to which some patients are
sensitive.5 These preparations are therefore of particular
use in patients developing nasal discomfort with more commonly
prescribed sprays.
Either betamethasone or fluticasone nasal drops are preferable to
the course of 20 mg oral prednisolone suggested by the authors We agree that many patients with allergic rhinitis can be treated
successfully in primary care but believe that more emphasis should be
placed on adequate initial examination of the patient and particularly
on referral to a specialist otolaryngologist or allergist should
initial treatment fail.
Although the 10-minute consultation on rhinitis serves as a
useful guide for treatment of this common condition, certain points
merit clarification.1
a treatment rarely given for allergic rhinitis even by specialists. Equally, the authors are unwise to suggest referral for immunotherapy as a realistic option in primary care, since this controversial technique is used in only a few centres.
Nataliebrookes{at}aol.com
Hesham Saleh
Ian Mackay
Department of Otorhinolaryngology, Charing Cross Hospital,
London W6 8RF
| 1. | Walker S, Sheikh A. 10-minute consultation. Rhinitis. BMJ 2002; 324: 403. (16 February.) |
| 2. | Sibbald B, Barnes G, Durham SR. Skin prick testing in general practice: a pilot study. J Adv Nurs 1998; 27: 442-444. |
| 3. | Graf P, Hallen H, Juto JE. Four-week use of oxymetazoline nasal spray (Nezeril) once daily at night induces rebound swelling and nasal hypersensitivity. Acta Otolaryngol 1995; 115: 71-75. |
| 4. | Daley-Yates PT, Baker RC. Systemic bioavailability of fluticasone propionate administered as nasal drops and aqueous nasal spray formulations. Br J Clin Pharmacol 2001; 51: 103-105. |
| 5. | Hallen H, Graf P. Benzalkonium chloride in nasal decongestive sprays has a long-lasting adverse effect on nasal mucosa of healthy volunteers. Clin Exp Allergy 1995; 25: 401-405. |
Article is unhelpful
EDITOR In over seven years as a consultant head and neck surgeon, I have
seen only two cases of sinonasal malignancy. In both, although nasal
obstruction was present, it was not the presenting symptom: that was
pain and facial swelling. There was no bleeding in either case.
The statement that patients with such symptoms warrant an urgent
specialist opinion, without reference to the relative frequencies of
the causative disease, is unhelpful and inappropriate.
The comment in the 10-minute consultation on rhinitis that
unilateral nasal obstruction and bloodstained discharge is an alarm
symptom of nasopharyngeal carcinoma is untrue.1 Unilateral
nasal obstruction and nose bleeds are extremely common nasal symptoms,
presenting either separately or together, and are usually due to a
deviation of the nasal septum. The occasions on which they might be due
to serious disease are vanishingly small. Furthermore, they are not
symptoms of nasopharyngeal carcinoma: it tends to present as a
unilateral serous otitis media.
Frimley Park Hospital, Camberley, Surrey GU16 5UJ
AMcco79794{at}aol.com
1.
Walker S, Sheikh A.
10-minute consultation. Rhinitis.
BMJ
2002;
324:
403. (16 February.)
© BMJ 2002