|
|
Characteristics of trials included in meta-analysis of continuous
subcutaneous insulin infusion versus intensive insulin
injections
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|
| Author |
No
of participants |
Mean (SD or range) age
(years) |
Mean (SD or range) duration of
diabetes (years) |
Duration of treatment
(months) |
Type of
pump |
Type of
insulin |
Injection regimen |
|
| Schiffrin,
19828 |
16 |
24.9
(8.8) |
10.4
(5.1) |
6 |
Mill
Hill |
Connaught/Lilly
regular |
Regular thrice
daily; isophane insulin at bedtime |
| Home,
19826 |
10 |
40.4 (7.3) |
23.5 (8.3) |
2.5 |
Mill
Hill, Auto-Syringe |
Pork Actrapid |
Regular thrice daily;
ultralente pm |
| Nathan, 19825 |
5 |
31
(5.7) |
7.4 (1.8) |
2-3 |
Auto-Syringe |
NA |
Regular thrice
daily; regular isophane insulin twice daily; ultralente before
breakfast |
| Schiffrin,
198411 |
24 |
13-20 |
9 |
4 |
Mill
Hill |
Connaught/Lilly regular |
Regular thrice daily; isophane
insulin pm/bedtime |
| Dahl-Jørgensen, 19867 |
15 |
26
(19-42) |
12.8 |
24 |
Nordisk |
Pork Velosulin |
Regular twice
daily; isophane insulin am/bedtime |
|
15 |
26
(18-32) |
12.8 |
|
Auto-Syringe |
|
|
| Helve,
198712 |
65 |
31.1 (1) |
12 (1) |
6 |
Nordisk
Auto-Syringe |
Velosulin Actrapid |
Multiple |
| Marshall,
198713 |
12 |
36 (21-50) |
18
(10-29) |
6 |
Nordisk |
Velosulin |
Regular twice daily; isophane
insulin twice daily/bedtime |
| Bak, 198714 |
20 |
24
(2) |
5.8 (3.8) |
6 |
Graseby |
Actrapid |
Regular thrice daily;
isophane insulin at bedtime |
| Saurbrey,
198816 |
21 |
32 (2.1) |
14.5
(1.4) |
2.5 |
Auto-Syringe, Medix |
NA |
Regular thrice or four
times daily; lente bedtime |
| Schmitz, 198917 |
10 |
36.5
(7.9) |
23.7 (2.9) |
6 |
Nordisk |
Velosulin |
Regular thrice
daily; isophane insulin at bedtime |
| Düsseldorf,
199018 |
47 |
32 (18-54) |
18
(3-44) |
24 |
Nordisk, Promedos |
NA |
Regular twice, thrice, or
four times daily |
|
49 |
|
|
|
Betatron,
Auto-Syringe |
NA |
Twice daily isophane insulin (or before
breakfast
injection/bedtime) |
| Hannaire-Broutin,
200019 |
41 |
43.5 (10.3) |
20.0
(11.3) |
4 |
MiniMed, Disetronic |
Lispro |
Thrice daily monomeric;
twice daily isophane insulin (or before breakfast
injection/bedtime) |
|
|
NA=data not available.
|
|
*
Regular=regular soluble or short acting insulin.
|
Participants on injections.
|
Participants on pump therapy.
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