Glycaemic control is better with continuous insulin infusion than injections

Glycaemic control in patients with type 1 diabetes is slightly better during continuous insulin infusion than during optimised insulin injection treatment. Pickup and colleagues (p 705) performed a meta-analysis of 12 randomised controlled trials involving 301 patients with type 1 diabetes allocated to insulin infusion and 299 allocated to insulin injection. They conclude that continuous subcutaneous insulin infusion is an effective form of intensive insulin that should lower the risk of microvascular complications. However, insulin pump treatment is unnecessary for most people with type 1 diabetes and should be reserved for those experiencing problems with optimised insulin injections.

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Relevant Article

Glycaemic control with continuous subcutaneous insulin infusion compared with intensive insulin injections in patients with type 1 diabetes: meta-analysis of randomised controlled trials

John Pickup, Martin Mattock, and Sally Kerry
BMJ 2002 324: 705. [Abstract] [Full Text] [PDF]