Prolonged use of ramipril prevents stroke

Ramipril reduces the incidence of stroke in patients at high risk, despite an only modest reduction in blood pressure. Bosch and colleagues (p 699) report that the relative risk of any stroke was reduced by 32% in patients receiving ramipril compared with placebo, and the relative risk of fatal stroke was reduced by 61%. These benefits are observed even when patients received aspirin and other treatments lowering blood pressure.


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