Microdialysis has wide applicability for in vivo measurements

Microdialysis enables in vivo measurement of tissue chemistry and is feasible in virtually every human organ. According to Müller (p 588) it is currently being used to monitor brain ischaemia and metabolic control. This technique is also about to become a standard tool in drug monitoring and development. In the future, miniaturisation and online automisation of chemical assays will allow "bedside" microdialysis for assessing antibiotic penetration for infected organs and monitoring tissue metabolism in disease states.

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Relevant Article

Science, medicine, and the future: Microdialysis

Markus Müller
BMJ 2002 324: 588-591. [Extract] [Full Text] [PDF]