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Hepatitis C infection does not increase all cause mortality in the
first decade of infection, but those infected have an increased risk of
dying from a liver related cause, particularly if they consume excess
alcohol. Harris and colleagues (p 450) report on their cohort study of
924 British transfusion recipients infected with hepatitis C virus who
were traced during the "lookback" programme. They found that
testing positive for the viral ribonucleic acid, having acquired the
infection at an older age, and increasing years since transfusion were
associated with developing liver disease. Continuing observation of
this cohort will help determine the long term outcome of hepatitis C
infection.