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The finding in a free living population of a measurable independent
relation between eating frequency and lipid concentrations shows that
we need to consider not only what we eat but how often we eat. In men
and women in the EPIC-Norfolk cohort, concentrations of total
cholesterol and low density lipoprotein cholesterol were inversely
related to eating frequency despite higher intakes of energy and
nutrients in people eating more frequently. Titan et al (p 1286) found
that this association remained after adjustment for these and other
possible confounding factors, including obesity, alcohol intake,
cigarette smoking, and physical activity.