Botulinum toxin type A can control excessive sweating

Injecting the axillae with botulinum toxin type A reduced sweating by more than 80% at four weeks in patients with hyperhidrosis. In a multicentre randomised controlled trial, Naumann et al (p 596) found that the toxin was more effective than placebo in terms of number of responders, percentage decrease in sweating, and absolute sweat production. Patient satisfaction was high and adverse events were few. The treatment remained effective at 16 weeks. The authors say that botulinum toxin type A should replace current surgical and medical treatments for this disorder.


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Relevant Article

Botulinum toxin type A in treatment of bilateral primary axillary hyperhidrosis: randomised, parallel group, double blind, placebo controlled trial
M Naumann and N J Lowe
BMJ 2001 323: 596. [Abstract] [Full Text] [PDF]

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