BMJ 2001;322:829-830 ( 7 April )

Papers

Fatigue, alcohol, and serious road crashes in France: factorial study of national data

Editorial by Feyer

P Philip, consultant aF Vervialle, statistician bP Le Breton, statistician bJ Taillard, research assistant aJ A Horne, professor c

a Clinique du Sommeil, Centre Hospitalier Universitaire, Bordeaux 33076, France, b Service d'Études Techniques des Routes et Autoroutes, Bagneux, France, c Sleep Research Laboratory, Loughborough University, Loughborough LE11 3TU

Correspondence to: P Philip pierrephilip{at}compuserve.com

France has a high rate of road traffic crashes.1 Although driver fatigue may be an important factor,2-4 it has not been investigated in France, and no comparisons have been made with alcohol related crashes.5 We investigated the role of fatigue in serious road crashes using the French national database.1


    Methods and results
Top
Methods and results
Comment
References

We obtained data from the French Ministry of Transport on all road crashes during 1994-8 (640 670) in which at least one person was severely injured (confirmed by paramedics) or died. Crashes were attended by police officers, who completed a standard ministry questionnaire that covered time of incident, location, road and weather conditions, vehicles involved, mechanical defects, health of driver, and alcohol consumption as well as giving summaries of interviews and probable causes.

As crashes related to fatigue can be difficult to identify, we applied the strict criteria of Horne and Reyner to eliminate many of the confounding factors.2 We assessed only single vehicle crashes that occurred during good weather and road conditions on roads unrestricted by junctions. This excluded most urban road crashes (comprising most crashes), crashes involving pedestrians, and those in which the driver reported taking medication or was suspected to have used illicit drugs. This left 67 671 crashes for analysis.

We identified four categories of crash:

Alcohol related---Blood alcohol concentration >100 mg ethanol/1 l blood (breathalyser or blood analysis).

Fatigue related---Driver could have avoided crash but no avoidance taken (no braking or swerving), with blood alcohol concentration <100 mg/l.

Alcohol and fatigue related---Fatigue related crash with driver's blood alcohol concentration >100 mg/l.

No alcohol or fatigue---No fatigue; blood alcohol concentration<100 mg/l.

About 10% (6770) of the crashes were related to fatigue and 23% (15 670) to alcohol (table 1). These were subdivided into three periods: day (0700-1959), evening (2000-2359), and early morning (0000-0659). Alcohol related crashes were more likely to be fatal during the evening and early morning compared with the daytime (Wald's chi 2=4.88, P=0.02 for evening, chi 2=18.04, P< 0.01 for early morning), whereas fatigue related crashes were more likely to be fatal during the day than the early morning (chi 2= 5.37, P=0.02).


                              
View this table:
[in this window]
[in a new window]
 

Table 1.

For the whole 24 hours, and compared with all other non-alcohol related crashes, the relative risk of death in crashes related to fatigue was 1.65 (95% confidence interval 1.49 to 1.82, chi 2 =97.09, P=0.001). The risk of severe injuries was 1.5 (1.4 to 1.6, chi 2= 226.15, P=0.001).

For alcohol related crashes, the relative risk was 4.2 (3.9 to 4.4, chi 2= 2517, P=0.001) for death and 1.9 (1.8 to 2.0, chi 2=1057, P=0.001) for severe injuries. For alcohol and fatigue combined, the risk of death was 6.8 (5.7 to 8.0, chi 2 =678, P=0.001) and risk of severe injuries 2.6 (2.2 to 3.0, chi 2 =141, P=0.001).

We then ran a multivariate analysis on daytime crashes with death as the dependent variable and fatigue, physical handicap, distraction (driver alert but attending elsewhere), and weekend (versus weekday) as independent variables. For non-alcohol related crashes resulting in death, the significant factors were fatigue (odds ratio=1.57, 95% confidence interval 1.42 to 1.74, P<0.001), distraction (0.70, 0.61 to 0.82, P<0.001), and weekends (1.14, 1.05 to 1.23, P<0.001). For alcohol related crashes resulting in death, only fatigue was significant (1.41, 1.15 to 1.73, P<0.001).


    Comment
Top
Methods and results
Comment
References

We found that fatigue, especially when combined with alcohol, presents a particularly high risk of road crashes resulting in death or serious injury. This has been largely unrecognised in France and elsewhere. There was also a strong relation between time of day and cause of crash, with many alcohol related crashes occurring at night. However, it is likely that police officers will attribute such crashes only to alcohol, even when fatigue is present.

    Acknowledgments

We thank Annie Canel and Michel Labrousse, Service d'Études Techniques des Routes et Autoroutes, for help in organising and Bernard Bioulac, department of neurophysiology, Bordeaux University Hospital, for his support.

The paper was written jointly by PP, FV, JT, and JAH. PLB is the guarantor.

    Footnotes

Funding: This study was sponsored by the Service d'Études Techniques des Routes et Autoroutes.

Competing interests: None declared.


    References
Top
Methods and results
Comment
References

1. Observatoire National Interministériel de la Sécurité Routière. Bilan annuel statistiques et commentaires. Paris: Ministère des Transports, 1999.
2. Horne JA, Reyner LA. Sleep related vehicle accidents. BMJ 1995; 310: 565-567[Abstract/Free Full Text].
3. Philip P, Ghorayeb I, Stoohs R, Menny JC, Dabadie P, Bioulac B, et al. Determinants of sleepiness in automobile drivers. J Psychosomatic Res 1996; 41: 279-288[Medline].
4. Philip P, Taillard J, Guilleminault C, Quera Salva MA, Bioulac B, Ohayon M. Long distance driving and self induced sleep deprivation among automobile drivers. Sleep 1999; 22: 475-480[Medline].
5. Biecheler MB, Filou C, Fontaine H. Conduite automobile et accidents liés à l'alcool. Références et résultats 1985 et 1995. Arceuil: INRETS Publishers, 1995.

(Accepted 21 December 2000)


© BMJ 2001

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to StumbleUpon StumbleUpon   Add to Technorati Technorati    What's this?

Relevant Articles

Awareness of driving while sleepy and road traffic accidents: prospective study in GAZEL cohort
Hermann Nabi, Alice Guéguen, Mireille Chiron, Sylviane Lafont, Marie Zins, and Emmanuel Lagarde
BMJ 2006 333: 75. [Abstract] [Full Text] [PDF]

The BMJ: competing with football
BMJ 2001 322: 0. [Full Text] [PDF]

The BMJ: competing with football
BMJ 2001 322: 0. [Full Text] [PDF]

Fatigue: time to recognise and deal with an old problem
Anne-Marie Feyer
BMJ 2001 322: 808-809. [Extract] [Full Text] [PDF]

This article has been cited by other articles:

  • Patil, S. P. (2009). Excessive Daytime Sleepiness: Medicolegal Aspects. ACCP Sleep Med Brd Rev 4: 139-152 [Full text]  
  • Radun, I., Summala, H. (2007). Breath analyser market is set to grow: a road safety perspective. Eur J Public Health 17: 537-537 [Full text]  
  • Nabi, H., Gueguen, A., Chiron, M., Lafont, S., Zins, M., Lagarde, E. (2006). Awareness of driving while sleepy and road traffic accidents: prospective study in GAZEL cohort. BMJ 333: 75- [Abstract] [Full text]  
  • Philip, P., Taillard, J., Moore, N., Delord, S., Valtat, C., Sagaspe, P., Bioulac, B. (2006). The effects of coffee and napping on nighttime highway driving: a randomized trial.. ANN INTERN MED 144: 785-791 [Abstract] [Full text]  
  • Horne, J A, Reyner, L A, Barrett, P R (2003). Driving impairment due to sleepiness is exacerbated by low alcohol intake. Occup. Environ. Med. 60: 689-692 [Abstract] [Full text]  
  • Leproult, R., Colecchia, E. F., Berardi, A. M., Stickgold, R., Kosslyn, S. M., Van Cauter, E. (2003). Individual differences in subjective and objective alertness during sleep deprivation are stable and unrelated. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284: R280-R290 [Abstract] [Full text]  
  • Akerstedt, T, Knutsson, A, Westerholm, P, Theorell, T, Alfredsson, L, Kecklund, G (2002). Work organisation and unintentional sleep: results from the WOLF study. Occup. Environ. Med. 59: 595-600 [Abstract] [Full text]  
  • Connor, J., Norton, R., Ameratunga, S., Robinson, E., Civil, I., Dunn, R., Bailey, J., Jackson, R. (2002). Driver sleepiness and risk of serious injury to car occupants: population based case control study. BMJ 324: 1125-1125 [Abstract] [Full text]  
  • (2001). Friends Don't Let Friends Drive Sleepy!. JWatch Emergency Med. 2001: 8-8 [Full text]  
  • Feyer, A.-M. (2001). Fatigue: time to recognise and deal with an old problem. BMJ 322: 808-809 [Full text]  

Rapid Responses:

Read all Rapid Responses

Fatigue or inattention?
Brian S Alper
bmj.com, 8 Apr 2001 [Full text]
Data do not warrant conclusions
Thomas V Holohan
bmj.com, 13 Apr 2001 [Full text]
Fatigue and Alcohol: Factoring out the Pathogen
Elihu D Richter
bmj.com, 13 May 2001 [Full text]



Access jobs at BMJ Careers
Whats new online at Student 

BMJ